Fertility medicine keeps moving forward. Now fertility tech is catching up.
We didn't just build a form. We built a new standard.
For decades, most programs didn’t offer donor updates at all. When they did, they relied on brief 10–15 minute surveys that missed critical health details. Over time, clinics closed, records were lost, donors moved or changed emails, and parents became unreachable — leaving donor-conceived people without the vital information they need and deserve. Donor 21 changes that.
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Based on science and evidence.
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73% of medical diagnoses are based on health history¹
Having an accurate health history for your child is critical. Donor’s health evolves over the years, yet many donor-conceived families never receive these updates. Donor 21 keeps them current and available when care depends on it.
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94% of egg donors were not asked for medical updates²
In a 2025 U.S. study, 94.3% of donors reported no medical follow-up, yet one in four had new health changes to share. Now donors can easily update their health records anytime.
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84% of donors’ health histories were missing key details³
Brief online questionnaires often miss critical information, leaving inherited risks undiscovered. Donor 21 uses a three-generation pedigree method — verifying family knowledge and following up on key findings — to create the most complete history possible.
¹ Tsukamoto T et al., Int J Med Educ., 2012.
² Adlam K et al., Fertil Steril., 2025.
³ Varriale C et al., J Assist Reprod Genet., 2025.

The evidence was clear. Families deserved a better system — so we made one.

Built for Families. Backed by Experts.
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Our founder drew from her over 20 years of work in the fertility space and her medical training at the Yale School of Medicine to build Donor 21 using the same gold-standard process taught in top medical programs and outlined by ASRM and SART for collecting detailed family and medical histories — creating three-generation pedigrees, capturing traits, and documenting risk factors the way physicians and genetic counselors do. The result is a living record that evolves with each family and reflects the whole picture of wellness — including lifestyle, environment, mental health, and family history.
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Informed by real experience and expertise.
Fertility Doctors
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Geneticists
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Pediatricians
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Fertility Lawyer​​​
Mental Health Specialists
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Parents​
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Donors
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Donor Conceived Offspring





Offspring
Tailored solutions for every journey.


Donors


Professionals
Recipients
The Moving Story Behind Donor 21
So much more than just health updates -
The Heart of Donor 21
In addition to robust health reports, we added meaningful features to support connection, memory, and peace of mind.
Memory Box for
memory preservation
Parents can save photos, letters, and milestones each year. After 21 years, Donor 21 transforms these memories into a beautiful keepsake book to share with their child.
Memory Exchange & Messaging
Stay connected through yearly updates, photos, and messages — between you, your donor, and donor-conceived siblings who share your story.
Storage Vault for
Contract & Files
Preserve donor profiles, photos, contracts, and documents securely — always organized, never lost, and visible only to those you grant permission.

Join the mission. Register as a professional partner.
As a Donor 21 professional partner, you can securely provide every recipient with ongoing donor health updates and family connection tools — at no cost to your practice. And we will manage updating donor and recipient contact information, cycle histories and outcomes, and provide you with flagged notifications if there are any changes you should be aware of all at no cost to you.
